Laboratory tests during direct oral anticoagulant treatment? Yes

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Laboratory tests during direct oral anticoagulant treatment? No.

The anticoagulant effect of Dabigatran etexilate, Rivaroxaban, and Apixaban is dose-predictable, steady, and little influenced by diet and drugs [1]. Thus, similar to lowmolecular weight heparin, laboratory tests have been unnecessary to evaluate such direct oral anticoagulant drugs (DOACs) in trials on thromboprophylaxis (Table 1). Nor such testing was needed in patients with atrial fibrillati...

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Safety of percutaneous coronary intervention during uninterrupted oral anticoagulant treatment.

AIMS Uninterrupted anticoagulation (UAC) is assumed to increase bleeding and access-site complications. A common consensus is to postpone percutaneous coronary interventions (PCI) to reach international normalized ratio (INR) levels < 1.5-1.8. METHODS AND RESULTS To assess the safety and feasibility of UAC, we analysed retrospectively all consecutive patients (n = 523) on warfarin therapy ref...

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Overview of direct oral anticoagulant therapy reversal.

PURPOSE Strategies for the management of bleeding complications and facilitation of an invasive procedure in patients receiving direct oral anticoagulants (DOACs) are reviewed. SUMMARY The DOACs provide clinical advantages versus vitamin K antagonists, including fixed dosing with no routine coagulation monitoring and evidence of a lower risk of bleeding. However, as with all anticoagulants, t...

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Survey of oral anticoagulant treatment in children.

AIMS To find out which children are treated with oral anticoagulants and how their treatment is controlled in the United Kingdom. METHODS Two questionnaires were used. The first was sent to general haematologists and the other to paediatric cardiologists and cardiac surgeons. RESULTS There were 273 (58%) replies to the first questionnaire. Most children were treated because of artificial ca...

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Normalized Ratio (INR) Determination with a Laboratory-Based System for Control of Oral Anticoagulant Treatment

Objective: To evaluate the accuracy and precision of INR determination of CoaguCheck XS compared to the standard laboratory method among patients with long-term warfarin therapy. Methods: 39 patients receiving long-term warfarin were eligible in this study. Parallel INR measurements were performed. Capillary INR (INR_C) measurements were determined with CoaguCheck XS and venous INR (INR_V) were...

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ژورنال

عنوان ژورنال: Internal and Emergency Medicine

سال: 2013

ISSN: 1828-0447,1970-9366

DOI: 10.1007/s11739-013-0949-3